Publications & Podcasts

Articles featuring the Ayer Neuroscience Institute Headache Center


ShiraTronics Completes Australian Pilot Study Enrollment; Prepares for Pivotal Clinical Study

Co-principal investigator Dr. Brian Grosberg will lead the upcoming U.S. study of RELIEV-CM2, a device for treatment of chronic migraine.

PR Newswire | February 6, 2024

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PR Newswire


New Ways to Fight Migraine

Researchers still are trying to unravel the mystery of the intense form of head pain known as migraine. If you suffer from this debilitating neurological condition, relief is never as simple as taking aspirin, NSAIDs or other painkillers. Migraine is a highly individualized disorder that needs a personalized medication regimen…and even that may not work all the time. But there is hope—new classes of drugs are emerging along with new ways of using existing medications. Bottom Line Personal spoke with migraine specialist Brian M. Grosberg, MD, to learn more about the new treatments and what is coming in the future.

BottomLineInc | February 4, 2024

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Moving Beyond Pain: Uncovering Migraine Patients' Surprising Acvitity Trends with Dr. Maoz Halevy

Talking Head Pain Podcast | November 21, 2023

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Talking Head Pain podcast

How Safe Is OnabotulinumtoxinA for Pregnant Women With Migraine? A Longitudinal Study Offers Some Answers

Brian Grosberg, MD, FAHS, medical director of the Hartford healthcare Headache Center in Connecticut, is quoted in this article about a study assessing migraine during pregnancy.

NeurologyToday | June 1, 2023

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Treatment Challenges for Migraine During Pregnancy

Video: Brian Grosberg, MD, FAHS, medical director of the Hartford healthcare Headache Center in Connecticut, discusses the significance of findings from a study assessing migraine during pregnancy.

NeurologyLive | February 15, 2023

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Knowledge and Comfort in Treating Migraine During Pregnancy

Studies show that migraine is associated with several maternal and fetal health complications during pregnancy. Treating migraine during this period can be difficult because of the lack of clinical trials investigating the risks related to specific treatments. Allison Verhaak, PhD, and colleagues, recently had a published survey study of 92 women's healthcare providers where results identified a variety of comfort levels for migraine care during pregnancy.

NeurologyLive | February 3, 2023

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Clinical Provider Survey Reveals Varied Levels of Comfort for Migraine Treatment During Pregnancy

“Migraine treatment during pregnancy can be challenging for many reasons, including risks associated with certain medications and lack of clinical trials,” says Allison Verhaak, PhD, clinical psychologist, Headache Center. Allison is lead author of a recent survey study of 92 women's healthcare providers, 91% of whom specialized in general obstetrics and gynecology.

NeurologyLive | February 2, 2023

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“It’s Just a Migraine”

Dr. Allison Verhaak and her team recommend additional education around migraine management among women’s health care providers to improve patient care in a 2020 paper that was mentioned in this article from article from Boston University’s School of Public Health.

Public Health Post | Oct. 31, 2022

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Public Health Post

Theranica Achieves Positive Results in Placebo-Controlled Pivotal Trial of Nerivio® for Preventive Treatment of Migraine

"These data demonstrate Nerivio's potential to provide a new non-pharmacological preventive treatment option for people with migraine", said Brian Grosberg, MD, Director of the Hartford Healthcare Headache Program, who served as the primary investigator of the study.

PR Newswire | Oct. 18, 2022

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Potential New Neuromodulation Treatment for Migraines

Dr. Brian Grosberg is quoted in this story about a non-invasive treatment for episodic migraines. A smartphone-enabled device, cleared by the US Food and Drug Administration in early 2021, uses technology to trick the brain into releasing the neurotransmitters serotonin and noradrenaline that can help ease migraine pain.

MedScape | June 13, 2022

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Important Announcement: Migraine Research Foundation

Announcement regarding the HHC Headache Center carrying on the work of the Migraine Research Foundation.

Headache and Migraine News | Jan. 8, 2022

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New Treatments for Migraine

Dr. Grosberg contributed to the Nov. 15, 2021 issue of Bottom Line Personal regarding New Treatments for Migraine.

BottomeLineInc. | Nov. 15, 2021

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Nerivio Device gets FDA approval

Nerivio is a wearable device that stimulates small nerves in the upper arm to relieve migrains. Dr. Grosberg is quoted in several articles regarding the device. | Pain Reports, November 2021 | October 25, 2021 | October. 18, 2021

Nerivio Treatment

HEADucation Inititative

The Headache Center's Allison Verhaak, PhD, Clinical Health Psychologist and Brian Grosberg, MD, FAHS, Director, Hartford Healthcare Headache Center Director, talk about “HEADucation”, an online, case-based, live and interactive lecture series for primary care internal medicine residents and neurology residents, created by the Headache Center.

Society for Health Psychology | Summer, 2021 Issue

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Can you get a headache from treating your headache? Medication overuse explained.

Dr. Brian Grosberg is interviewed regarding medication overuse and how your head pain can rebound when these medications wear off.

SingleCare | August 17, 2021

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Virtual Roller Coaster Ride Study Brings New Insights Into Migraine

Dr. Brian Grosberg is interviewed regarding a new study that shows people who get migraines will likely feel motion sickness and dizziness after a virtual roller coaster ride, compared with people who don't get migranes.

WebMD | July 22, 2021

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Migraine Highlights From 2021 AHS Virtual Scientific Meeting

Dr. Brian Grosberg reviews late-phase trial data demonstrating the efficacy of the oral CGRP antagonists atogepant and rimegepant for migraine prevention. He also reports on a summary of data from the CaMEO survey indicating that oral preventive therapies for migraine are greatly underutilized despite high interest among patients, and he shares results from a new patient satisfaction survey that reveals how patients viewed telehealth measures for migraine care accessed during the COVID-19 pandemic.

MedScape | June 25, 2021

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7 At-Home Solutions For Migraine Relief

Dr, Grosberg explains that though a migraine can be debilitating, a few adjustments can help ease the pain.

Allure | May 3, 2021

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For Rising Number of People, Obesity Is a Literal Headache

Dr. Grosberg is quoted in this story about the growing numbers of people are developing a potentially blinding type of weight-linked headache that was once considered rare.

HealthDay | January 22, 2021
US News | January 22, 2021

Migraine: What Your Doctor Doesn’t Know

Dr. Grosberg is quoted in this EverydayHealth story about new findings suggesting that doctors who treat women have significant knowledge gaps that could compromise the care of this debilitating condition.

EverydayHealth | January 7, 2021

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Ask The Experts: Brian Grosberg & Kiran Rajneesh, MD

"During the COVID-19 pandemic, I've had an increase in migraine attacks. Is stress likely to blame?"

HealthCentral Chronic Migraine | October 2, 2020

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Migraine Guide

Dr. Grosberg is quoted in the story "How I tamed my migraines" in the Summer, 2020 issue of HealthCentral's "Guide to Living with Migraine"

Migraine Monitor | Summer, 2020

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New Nondrug Relief for Migraines

Dr. Grosberg contributed the story "New Nondrug Relief for Migraines" in the April 15 issue of Bottom Line Personal.

BottomLineInc. | April 15, 2020

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Ask the Expert

Dr. Brian Grosberg was featured in an article titled “Ask the Expert: Brian Grosberg, MD Q&A” in HealthCentral Guide.

HealthCentral Guide | December, 2019

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W. Hartford-linked migraine device wins FDA approval

Dr. Grosberg is quoted in this new story regarding FDA approval of the Nerivio Migra® device.

Hartford Business Journal | June 10, 2019

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FDA Grants Theranica De Novo to Market First Smartphone-controlled Acute Migraine-relief Wearable Device

Dr. Grosberg is quoted in this press release regarding FDA approval of Nerivio Migra®, a smartphone-controlled device developed by Theranica, a bio-medical technology company developing advanced electroceuticals for migraine and other pain disorders.

PR Newswire | May 28, 2019

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Latest Device Now FDA Approved for Teens with Migraine

The US Food and Drug Administration (FDA) just approved a new device for migraine prevention in teens: eNeura’s sTMS. This approval expands the therapeutic options for both adults and children 12 years of age and older. Dr. Grosman demonstrated the device during the 2017 Migraine World Summit.

Migraine Again | March 1, 2019

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New Relief for Migraines

Advances in treating the mother of all headaches, from Botox to better drugs. Dr. Grosberg is a contributor to this story posted on

AARP | February 1, 2019

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This is why you get more migraines in the winter

“Weather factors may interact with each other and operate synergistically to trigger a headache,” says Brian Grosberg, MD, director of Hartford HealthCare Ayer Neuroscience Institute Headache Center.

Yahoo! LifeStyle | December 18, 2018

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Nerivio Migra Device for Acute Migraine Treatment

Brian Grosberg, MD, director of the Hartford Healthcare Headache Center in Connecticut and lead investigator on the Nerivio Migra trial, provides some insight into this new treatment.

NeurologyLive | November 16, 2018

Menstrual Migraines

“Menstrual migraine affects more than 50 percent of female migraine patients, accounting for about 12 million women annually,” says doctor Brian Grosberg, MD.

Yahoo! LifeStyle | November, 2018

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Theranica Announces Results from Pivotal Study of Device for Treating Acute Migraine

Dr. Brian Grosberg, MD, Director of the Hartford Healthcare Headache Center in Connecticut, is lead  Principal Investigator of a study for Nerivio Migra, a non-invasive neuromodulation device that works with a phone app to deliver stimulation through the arm to treat acute migraines.

November, 2018

Migraine Guide

Dr. Grosberg is quoted in two stories in the Nov. 2018 issue of HealthCentral's "Migraine Guide", “The 411 on Migraine” and “All About Therapies”.

Health Central | November, 2018

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Promise and Pitfalls of Preventing Migraine With CGRP Inhibitors

Dr. Grosberg is quoted in this story about new medical treatments available for migraines.

MD Magazine | July, 2018

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Perceived triggers of primary headache disorders: A meta-analysis

Dr. Pellegrino co-authored this study that appeared in the headache journal Cephalalgia.

Cephalalgia | May, 2018

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Nutraceuticals for Migraine Treatment

Dr. Chua was interviewed by the American Migraine Foundation regarding “Nutraceuticals for Migraine Treatment”.

American Migraine Foundation | May, 2018

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8 Headache Cures You Can Try Right Now

Dr. Grosberg recommends a breathing technique to help alleviate headache pain in this FamilyCircle story.

FamilyCircle | April, 2018

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Current Treatment Options: Headache Related to Menopause - Diagnosis and Management

Dr. Chua and colleagues’ recent paper published in Current Treatment Options in Neurology entitled “Current Treatment Options: Headache Related to Menopause—Diagnosis and Management “ was highlighted by the American Headache Society‘s ‘Headache in the News’.

Current Treatment Options in Neurology | March, 2018

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6 Illnesses With A Mind-Body Connection That Can’t Be Ignored

Brooke Pellegrino was interviewed for Women's Health magazine about the "mind-body connection" between many seemingly unrelated mental and bodily issues—many seemingly unrelated on the surface.

Women's Health | March, 2018

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13 Foods That Can Make Your Headaches Worse

If you’re consistently suffering from headaches or are prone to migraines, the culprit could be in your kitchen. Here is a list of foods that may trigger headaches.

Readers Digest | February, 2018

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Need for Speed: The Effects of an Expedited FDA Approval Process

Dr. Grosberg is quoted in this MD Magazine article about the FDA using expedited pathways to cut down the time it takes to conduct clinical reviews for new drugs.

MD Magazine | December 21, 2017

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Migraine Study Tests Pain Relieving Effects of Armband

More solutions are on the horizon for migraine sufferers. One option that researchers are studying that will hopefully help many of us who do not respond to medication, cannot take anything, have monthly medication limits, or want another treatment possibility. The option would be an armband stimulator that could abort a migraine attack. Dr. Grosberg explains how it would work. | November 15, 2017

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Central Region Radiologist Published in Prestigious Journal

Dr. Jignesh Modi, neuroradiologist with Midstate Radiology Associates, contributed to a recently published article in the Journal of Neurosurgery about intermediate and high-risk meningiomas, tumors that are found in the membranes surrounding the brain and spinal cord.

The American College of Radiology directed a meningioma brain tumor trial over several years, which included meningioma patients from medical centers across the United States and Canada. Last month, Dr. Modi published results of the phase II trial for intermediate-risk meningioma treatment outcomes, which will serve as a guideline for further management of this difficult-to-treat tumor. He will continue to be the co-primary investigator for the phase-three trial, which is already underway.

Dr. Modi joined Hartford HealthCare in 2016 and spends much of his time collaborating with the Ayer Neuroscience Institute.

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32 Everyday Habits That Will Reduce Your Risk of Headaches - Guaranteed

Headaches can really throw a wrench in the best-laid plans, but these tips from experts, including Dr. Brian Grosberg, can help drastically reduce your risk of experiencing one ... ever.

Reader’s Digest | August, 2017

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Electric Stim Armband May Reduce Migraine Pain

New pilot study finds that Theranica's electrical stimulation device, Nerivio Migra, is able to reduce migraine pain better than sham stimulation. The device is worn on the arm.

Practical Pain Management | June 27, 2017

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Migraine and Anxiety: An Interview with Psychologist Brooke Pellegrino

How common is anxiety in those with migraines? When does it warrant treatment? Hartford HealthCare psychologist Brooke Pellegrino answers the basics for's Lisa Robin Benson - and you! | May 17, 2017

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15 Signs Your Headache Could Be Something Way Worse

Nearly everyone gets headaches—from dehydration, allergies or just because you're overworked and overtired. Most are nothing to be worried about, except when they are. Dr. Brian Grosberg gives you the scoop on your head pain: What it means and how to know if you need medical attention.

Reader’s Digest | May, 2017

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What Your Weight Has to Do with Migraines

Your weight may influence your risk of experiencing debilitating migraine headaches, a new review of research suggests. Brian M. Grosberg, MD, Director of the Hartford HealthCare Headache Center in Hartford, Conn., reviewed the study for Reader’s Digest.

Reader’s Digest | May, 2017

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A New Research Grant Studies a Severe Form of Migraine

The study, which is projected to take about three years, aims to discover which patients will respond to which medications in treating something called status migrainosus. Co-researcher is Brian Grosberg, MD, Director of the Hartford HealthCare Headache Center. | January 16, 2017

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This Is the Exact Reason Why Your Hair Hurts

Features commentary by Dr. Brian Grosberg, Director of Hartford HealthCare Headache Center.

Allure Magazine | January 15, 2017

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Headache Specialists Explore Underlying Causes, Personalized Treatments

Dr. Brian Grosberg explains that more than 300 types of headaches have been identified, but they still aren't well understood.

Hartford Magazine | August 21, 2016

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What Doctors Tell Their Friends About Headaches

Dr. Brian Grosberg is interviewed for this June 2016 Redbook Magazine story.

Redbook Magazine | June, 2016

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Not Your Typical Headache

Dr. Brian Grosberg is interviewed for this June 2016 Good Housekeeping Magazine story.

Good Housekeeping | June, 2016

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About the Headache Center

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