Preventive Cardiology (iSCAD)

Title: The International Spontaneous Coronary Artery Dissection (iSCAD) Registry
Area/disease: SCAD
Department: Preventive Cardiology

Sponsor(s): SCAD Alliance

Spontaneous coronary artery dissection (SCAD) is a rare but important cause of acute myocardial infarction in otherwise healthy persons without traditional risk factors for heart disease.

While it can affect both sexes and affect older persons as well, the typical SCAD patient is a woman in her 40s to 50s or a woman who is pregnant or immediately post-partum. The optimal modes of diagnosis, management, and follow up of patients with SCAD are still being investigated and studies have been limited by small numbers in single institution registries.

The ultimate goal of iSCAD is to facilitate the development of best practices and clinical guidelines for the ultimate goal of preventing SCAD or its recurrence.

Inclusion Criteria:

  1. 18 Years of age or older.
  2. Diagnosis of SCAD or history of SCAD based on coronary angiography, either catheter-based or coronary CTA.
  3. Suspected SCAD by coronary angiography.

Exclusion Criteria:

  1. Coronary dissection in association with atherosclerosis or as a result of iatrogenic injury.
  2. Inability to provide informed consent.
  3. Inability to complete study-related patient questionnaires.
  4. Inability to understand and complete patient questionnaires independently.

Location(s): Patients that will be specifically recruited for enrollment include:

  1. Inpatients at Hartford Hospital during acute presentation of SCAD.
  2. In outpatient HHC clinics of the Investigators.

Contact(s): Erika Zahina, 860-972-3561,