Research News

IOL Study, Funded by $1 Million Grant, Focuses on Repeat Suicide Attempts

Psychiatric inpatients with prior suicide attempts are at particularly high risk to commit suicide, especially within the first few months after discharge. In this study, researchers at the Institute of Living’s Anxiety Disorders Center will examine whether a brief cognitive-behavioral therapy (CBT) can benefit this vulnerable population.  They will enroll 200 inpatients admitted following a suicide attempt. Participants will be randomly assigned to receive either CBT or Treatment as Usual. They will follow up with patients each month for 6 months after discharge. This study will be the first to establish an empirically-supported behavioral intervention for suicide prevention in suicidal inpatients and will be the foundation for future trials to accomplish dissemination and implementation of this treatment across health care systems. 

The Anxiety Disorders Center at the Institute of Living seeks to provide evidence-based psychological treatments to patients with a range of anxiety and mood disorders, and to conduct meaningful research on the nature and treatment of these disorders.  Under the direction of Dr. David Tolin, the Anxiety Disorders Center has been one of the Institute of Living’s centers of excellence for nearly 20 years.

Recent Publications

Abdelraouf K,Almarzoky Abuhussain S,Nicolau DP|In vivo pharmacodynamics of new-generation beta-lactamase inhibitor taniborbactam (formerly VNRX-5133) in combination with cefepime against serine-beta-lactamase-producing Gram-negative bacteria.|The Journal of antimicrobial chemotherapy

Babich O,Sukhikh S,Pungin A,Ivanova S,Asyakina L,Prosekov A|Modern Trends in the In Vitro Production and Use of Callus, Suspension Cells and Root Cultures of Medicinal Plants.|Molecules (Basel, Switzerland)

Battaglini D,Motos A,Li Bassi G,Yang H,Pagliara F,Yang M,Aguilera Xiol E,Meli A,Bobi J,Frigola G,Senussi T,Idone F,Travierso C,Chiurazzi C,Fernandez-Barat L,Rigol M,Ramirez J,Pelosi P,Chiumello D,Antonelli M,Nicolau DP,Bringue J,Artigas A,Guerrero L,Soy D,Torres A|Efficacy of Telavancin in Comparison to Linezolid in a Porcine Model of Severe Methicillin-Resistant Staphylococcus aureus Pneumonia.|Antimicrobial agents and chemotherapy

Bertsimas D,Lukin G,Mingardi L,Nohadani O,Orfanoudaki A,Stellato B,Wiberg H,Gonzalez-Garcia S,Parra-Calderon CL,Robinson K,Schneider M,Stein B,Estirado A,A Beccara L,Canino R,Dal Bello M,Pezzetti F,Pan A|COVID-19 mortality risk assessment: An international multi-center study.|PloS one

Brewer JM,Tran A,Ali MI,Fusco D,Portereiko J,Hashim SW,Underhill D,Gates JD,Gluck J|Traumatic right atrial rupture bridge to definitive repair with extra-corporeal life support.|Trauma case reports

Caballero A,Mao W,McKay R,Hahn RT,Sun W|A Comprehensive Engineering Analysis of Left Heart Dynamics After MitraClip in a Functional Mitral Regurgitation Patient.|Frontiers in physiology

Chernikova TN,Bargiela R,Toshchakov SV,Shivaraman V,Lunev EA,Yakimov MM,Thomas DN,Golyshin PN|Hydrocarbon-Degrading Bacteria Alcanivorax and Marinobacter Associated With Microalgae Pavlova lutheri and Nannochloropsis oculata.|Frontiers in microbiology

Cilhoroz B,Giles D,Zaleski A,Taylor B,Fernhall B,Pescatello L|Validation of the Polar V800 heart rate monitor and comparison of artifact correction methods among adults with hypertension.|PloS one

Costa OS,Salam T,Duhig A,Patel AA,Cameron A,Voelker J,Bookhart B,Coleman CI|Specialist physician perspectives on non-medical switching of prescription medications.|Journal of market access & health policy

Costa OS,Thompson S,Ashton V,Palladino M,Bunz TJ,Coleman CI|Rivaroxaban versus warfarin for treatment and prevention of recurrence of venous thromboembolism in African American patients: a retrospective cohort analysis.|Thrombosis journal

Distaso MA,Bargiela R,Brailsford FL,Williams GB,Wright S,Lunev EA,Toshchakov SV,Yakimov MM,Jones DL,Golyshin PN,Golyshina OV|High Representation of Archaea Across All Depths in Oxic and Low-pH Sediment Layers Underlying an Acidic Stream.|Frontiers in microbiology

Gowdar S,Ahlberg AW,Rai M,Perucki WH,Felpel KD,Savino JA 3rd,Alter EL,Henzlova MJ,Duvall WL|Risk stratification with vasodilator stress SPECT myocardial perfusion imaging in patients with elevated cardiac biomarkers.|Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Guo N,Wang Z,Bow LM,Cui X,Zhang L,Xian W,Sun H,Tian J|Cardiac Inotropes Offer Protection of Renal Function in Patients with Kidney Transplantation.|Kidney & blood pressure research

Hargrove D,Liang B,Kashfi-Sadabad R,Joshi GN,Gonzalez-Fajardo L,Glass S,Jay M,Salner A,Lu X|Tumor-mesoporous silica nanoparticle interactions following intraperitoneal delivery for targeting peritoneal metastasis.|Journal of controlled release : official journal of the Controlled Release Society

Henzlova MJ,Duvall WL|Temporal changes in cardiac SPECT utilization and imaging findings: Where are we going and where have we been?|Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Hernandez AV,Roman YM,Pasupuleti V,Barboza JJ,White CM|Update Alert 3: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19.|Annals of internal medicine

Hyatt CJ,Calhoun VD,Pittman B,Corbera S,Bell MD,Rabany L,Pelphrey K,Pearlson GD,Assaf M|Default mode network modulation by mentalizing in young adults with autism spectrum disorder or schizophrenia.|NeuroImage. Clinical

Kirker E,Korngold E,Hodson RW,Jones BM,McKay R,Cheema M,Heimansohn D,Moainie S,Hermiller J,Chatriwalla A,Saxon J,Allen KB|Transcarotid Versus Subclavian/Axillary Access for Transcatheter Aortic Valve Replacement With SAPIEN 3.|The Annals of thoracic surgery

Kois AK,Nicolau DP,Kuti JL|Unresolved issues in the identification and treatment of carbapenem-resistant Gram-negative organisms.|Current opinion in infectious diseases

Kumar S,Curran JE,Espinosa EC,Glahn DC,Blangero J|Highly efficient induced pluripotent stem cell reprogramming of cryopreserved lymphoblastoid cell lines.|Journal of biological methods

Lysaker PH,Gagen E,Klion R,Zalzala A,Vohs J,Faith LA,Leonhardt B,Hamm J,Hasson-Ohayon I|Metacognitive Reflection and Insight Therapy: A Recovery-Oriented Treatment Approach for Psychosis.|Psychology research and behavior management

Lysaker PH,Kukla M,Leonhardt BL,Hamm JA,Schnakenberg Martin A,Zalzala AB,Gagen EC,Hasson-Ohayon I|Meaning, integration, and the self in serious mental illness: Implications of research in metacognition for psychiatric rehabilitation.|Psychiatric rehabilitation journal

Macaluso M,Kinzie M,Cowley D,Houston LJ,DeJong S,Janssen F,Bentman A,Edgar L,Campbell B,Bowen L,Aronowitz J,Aoun E,Santiago P,Keepers G|The Psychiatry Milestones 2.0: How Did We Get from 1.0 to 2.0 and What Can Users Expect?|Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

Muradova E,Storonsky M,Ferenczi K,Santoro F|Eosinophilic granulomatosis with polyangiitis masquerading as hemorrhagic vesiculobullous herpes simplex infection.|International journal of dermatology

Patel SD,Desai N,Rane S,Patel N,Desai R,Mehta T,Ollenschleger MD,Nanda A,Starke RM,Khandelwal P|Trends in hospitalizations and epidemiological characteristics of adults Moyamoya disorder in the United States.|Journal of the neurological sciences

Patil S,Gonuguntala K,Rojulpote C,Kumar M,Corradi JP,Chen K|Delirium is an important predictor of mortality in elderly patients with ST-elevation myocardial infarction: insight from National Inpatient Sample database.|Coronary artery disease

Piscoya A,Ng-Sueng LF,Parra Del Riego A,Cerna-Viacava R,Pasupuleti V,Roman YM,Thota P,White CM,Hernandez AV|Efficacy and harms of remdesivir for the treatment of COVID-19: A systematic review and meta-analysis.|PloS one

Rousseau R,Weisberg DF,Gorero J,Parwani V,Bozzo J,Kenyon K,Smith C,Cole J,Curtis S,Forray A,Roberts JD|Utilization, financial outcomes and stakeholder perspectives of a re-organized adult sickle cell program.|PloS one

Salam T,Duhig A,Patel AA,Cameron A,Voelker J,Bookhart B,Coleman CI|Physicians' perspectives regarding non-medical switching of prescription medications: Results of an internet e-survey.|PloS one

Teevan C,Perriello E|Decreasing the Stress of Medication Management During Cardiac Arrest.|AACN advanced critical care

Tolin DF,Davies CD,Moskow DM,Hofmann SG|Biofeedback and Neurofeedback for Anxiety Disorders: A Quantitative and Qualitative Systematic Review.|Advances in experimental medicine and biology

Topiwala K,Tarasaria K,Staff I,Beland D,Schuyler E,Nouh A|Identifying Gaps and Missed Opportunities for Intravenous Thrombolytic Treatment of Inpatient Stroke.|Frontiers in neurology

Topiwala KK,Patel SD,Nouh AM,Alberts MJ|Novel GDF2 Gene Mutation Associated with Pulmonary Arteriovenous Malformation.|Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association