Research & Clinical Trials

The following research studies and clinical trials are being conducted by the Headache Center.


Theranica Research StudyTheranica Study

Principle Investigator: Dr. Brian Grosberg

We are currently recruiting for this study.

You may qualify to participate in a research study conducted at Hartford HealthCare Headache Center, of a home treatment for migraine using self-administered medical device. The study device is non-invasive and does not require taking medications. Compensation for your time and travel is available.

Frequently Asked Questions:

Q: What is the purpose of this study?
A: The clinical study is being conducted to test the effectiveness of an investigation device for the preventive treatment of migraine in patients who suffer from chronic migraine.

Q: Am I eligible to participate?
A: To be eligible to participate in this study, you must be 18-75 years old and be diagnosed with chronic migraine.

Q: If I am eligible and choose to participate, what will be my role in the study?
A: The investigational device is self-applied on the upper-arm and produces electrical stimulation in the nervous system that inhibits migraine headache. You will use the investigational device at home during an 8 week period and report you migraine attacks in your mobile phone diary app.

Q: Will I be paid for taking part in this research?
A: Qualified participants may receive compensation for time and travel

To participate, please contact the study team at 860.231.0718 or HeadacheResearch@hhchealth.org.


TRIUMPH Study

Principle Investigator: Dr. Brian Grosberg

We are currently recruiting for this study.

Frequently Asked Questions:

Q: What is the purpose of this study?
A: We are looking for people to take part in observational research to learn more about the medications used to prevent migraine headaches. Doctors will gather information about people’s usual case and how well their prescribed migraine medications work for them.

Q: Am I eligible to participate?
A: To be eligible to participate in this study, you must be 18 years of 18 or older, have been diagnoses with migraine, are starting a migraine prevention medication or switching to a different one, and have access to the internet on a computer or your mobile phone.

Q: If I am eligible and choose to participate, what will be my role in the study?
A: If you chose to take part, you will need to provide information about your health and treatments about every 6 months for up to 2 years. You will continue to have appointments with the doctor who usually treats your migraine headache, at the doctor’s office by telephone, or online.

You will also need to complete a diary, available online or via mobile app, for each migraine headache you have, plus a monthly questionnaire.

You will not receive any investigational drug as part of this research. You will continue to take any medication(s) prescribed by your doctor.

Q: Will I be paid for taking part in this research?
A: For taking part in this research, you may be paid up to a total of $150. You will receive the payment after you complete the study milestones.

To participate, please contact the study team at 860.231.0718 or HeadacheResearch@hhchealth.org.

Headache Center